Genomic inequalities and precision medicine
DOI:
https://doi.org/10.63618/omd/ssjm/v3/n2/46Keywords:
genomic inequalities, precision medicine, genetic diversity, health equity, epistemic justiceAbstract
The present study critically examines inequalities in population representation within genomic research and their impact on precision medicine. Through a systematic literature review of academic literature published between 2010 and 2024, major structural gaps that favor populations of European descent and exclude historically marginalized groups were identified. The results reveal significant biases in diagnoses, clinical predictions and therapeutic efficacy, especially affecting indigenous, Afro-descendant and Latin American communities. In addition, ethical and social consequences are evident that reinforce historical inequalities in access to biomedical knowledge and clinical benefits. The article concludes that precision medicine, far from democratizing health care, could deepen inequalities if it does not promote an effective inclusion of global genetic diversity. An ethical and structural reconfiguration of research models is proposed as a way towards real genomic justice.
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Copyright (c) 2025 Herrera-Sánchez, Priscila Jaqueline, López -Cudco, Leidy Liceth, Mina-Villalta, Geovanna Yamiley (Autor/a)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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